WebJul 1, 2024 · Biothiols such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) play an important role in regulating the vital functions of living organisms. However, … WebJan 13, 2024 · In recent years, research has fully shown that three kinds of biothiols (Cys, Hcy, GSH) mainly play the role in oxidative stress and maintaining cell homeostasis in cells, and that abnormal concentrations will lead to the occurrence of cardiovascular diseases, cancers, etc. Various fluorescent probes have shown unprecedented advantages in …
A Triple-Emission Fluorescent Probe for Discriminatory ... - PubMed
WebCom- mon biothiols include cysteine (Cys), homocysteine (Hcy)andglutathione(GSH).Amongthem,Cysasan essential thiol-containing amino acid involves many physiological processes including protein synthesis, detoxification, metabolism and post-translational modification [3]. WebThe Cys (or Hcy)-induced substitution–rearrangement cascade reaction and GSH-induced substitution reaction with the probe lead to the corresponding aminopyronin and … chef works from heaven
研究细胞内Cys和GSH合成途径关系的荧光探针 - 简书
WebFeb 11, 2015 · The discrimination of GSH from Cys and Hcy is achieved through two emission channel detection. The detection limit of probe for GSH reached 10 nM (3 ppb). The excellent sensitivity and... WebJun 1, 2014 · The simultaneous detection of GSH and Cys/Hcy is attributed to the significantly different rates of intramolecular S,N-acyl shift of their corresponding thioester adducts derived from 1. The utility of probe 1 has been demonstrated in various biological systems including serum and cells. WebJul 7, 2024 · Bio-thiols such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) play pivotal roles in various biological processes including protein synthesis, detoxification, metabolism, signal transduction and gene regulation. [ 1, 2] In addition, these bio-thiols are essential in regulating of the redox state of proteins and in protein structure. chef works lab coats